1.
The role of p53 in the DNA damage-related ubiquitylation of S2P RNAPII,
Barbara N Borsos, Vasiliki Pantazi, Zoltán G Páhi, Hajnalka Majoros, Zsuzsanna Ujfaludi, Ivett Berzsenyi, and Tibor Pankotai PLOS ONE doi: 10.1371/journal.pone.0267615
2.
Novel prognostic value of driver gene transcription signatures to characterise ccRCC,
Zsuzsanna Ujfaludi, Levente Kuthi, Gabriella Pankotai-Bodó, Bankó Sarolta Farkas Sükösd, Tibor Pankotai
Pathol. Oncol. Res. 28:1610345. doi: 10.3389/pore.2022.1610345
3.
The clinical significance of epigenetic and RNAPII variabilities occurring in clear cell renal cell carcinoma as a potential prognostic marker.
Ördög N, Borsos BN, Majoros H, Ujfaludi Z, Pankotai-Bodó G, Bankó S, Sükösd F, Kuthi L, Pankotai T.
Transl Oncol. 2022 Apr 10;20:101420. doi: 10.1016/j.tranon.2022.101420. Online ahead of print.
4.
Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster.
Páhi ZG, Kovács L, Szűcs D, Borsos BN, Deák P, Pankotai T.
Sci Rep. 2022 Apr 7;12(1):5870. doi: 10.1038/s41598-022-09703-x.
5.
Systematic overview on the most widespread techniques for inducing and visualizing the DNA double-strand breaks.
Berzsenyi I, Pantazi V, Borsos BN, Pankotai T.
Mutat Res Rev Mutat Res. 2021 Jul-Dec;788:108397. doi: 10.1016/j.mrrev.2021.108397. Epub 2021 Oct 29
6.
CDKL5 kinase controls transcription-coupled responses to DNA damage.
Khanam T, Muñoz I, Weiland F, Carroll T, Morgan M, Borsos BN, Pantazi V, Slean M, Novak M, Toth R, Appleton P, Pankotai T, Zhou H, Rouse J.
EMBO J. 2021 Dec 1;40(23):e108271. doi: 10.15252/embj.2021108271. Epub 2021 Oct 4.
7.
Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage.
Pantazi V, Berzsenyi I, Borsos BN, Pankotai T.
J Vis Exp. 2021 Aug 21;(174). doi: 10.3791/62175.
8.
SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response.
Majoros H, Borsos BN, Ujfaludi Z, Páhi ZG, Mórocz M, Haracska L, Boros IM, Pankotai T.
Int J Mol Sci. 2021 Aug 7;22(16):8500. doi: 10.3390/ijms22168500.
9.
Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria.
Ferenczi S, Solymosi N, Horváth I, Szeőcs N, Grózer Z, Kuti D, Juhász B, Winkler Z, Pankotai T, Sükösd F, Stágel A, Paholcsek M, Dóra D, Nagy N, Kovács KJ, Zanoni I, Szallasi Z.
Mol Ther Methods Clin Dev. 2020 Nov 20;20:218-226. doi: 10.1016/j.omtm.2020.11.010. eCollection 2021 Mar 12.
10.
Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair.
Borsos BN, Majoros H, Pankotai T.
Cancers (Basel). 2020 Jun 18;12(6):1617. doi: 10.3390/cancers12061617.
11.
Emerging Roles of Post-Translational Modifications in Nucleotide Excision Repair.
Borsos BN, Majoros H, Pankotai T.
Cells. 2020 Jun 15;9(6):1466. doi: 10.3390/cells9061466.
12.
PARylation During Transcription: Insights into the Fine-Tuning Mechanism and Regulation
Zoltán G. Páhi, Barbara N. Borsos, Vasiliki Pantazi, Zsuzsanna Ujfaludi and Tibor Pankotai
Cancers 2020, 12(1), 183; https://doi.org/10.3390/cancers12010183
13.
Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming.
Gyukity-Sebestyén E, Harmati M, Dobra G, Németh IB, Mihály J, Zvara Á, Hunyadi-Gulyás É, Katona R, Nagy I, Horváth P, Bálind Á, Szkalisity Á, Kovács M, Pankotai T, Borsos B, Erdélyi M, Szegletes Z, Veréb ZJ, Buzás EI, Kemény L, Bíró T, Buzás K.
Front Immunol. 2019 Oct 18;10:2459. doi: 10.3389/fimmu.2019.02459. eCollection 2019
14.
Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells.
Harmati M, Gyukity-Sebestyen E, Dobra G, Janovak L, Dekany I, Saydam O, Hunyadi-Gulyas E, Nagy I, Farkas A, Pankotai T, Ujfaludi Z, Horvath P, Piccinini F, Kovacs M, Biro T, Buzas K.
Sci Rep. 2019 Oct 25;9(1):15329. doi: 10.1038/s41598-019-51778-6.
15.
Quantification of DNA damage induced repair focus formation via super-resolution dSTORM localization microscopy.
Varga D, Majoros H, Ujfaludi Z, Erdélyi M, Pankotai T.
Nanoscale. 2019 Aug 1;11(30):14226-14236. doi: 10.1039/c9nr03696b.
16.
WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.
Caron P, Pankotai T, Wiegant WW, Tollenaere MAX, Furst A, Bonhomme C, Helfricht A, de Groot A, Pastink A, Vertegaal ACO, Luijsterburg MS, Soutoglou E, van Attikum H.
Genes Dev. 2019 Jun 1;33(11-12):684-704. doi: 10.1101/gad.321943.118. Epub 2019 May 2.
17.
SerpinB2 is involved in cellular response upon UV irradiation.
Majoros H, Ujfaludi Z, Borsos BN, Hudacsek VV, Nagy Z, Coin F, Buzas K, Kovács I, Bíró T, Boros IM, Pankotai T.
Sci Rep. 2019 Feb 26;9(1):2753. doi: 10.1038/s41598-019-39073-w.
18.
Chicken or the Egg: Microbial Alterations in Biopsy Samples of Patients with Oral Potentially Malignant Disorders.
Decsi G, Soki J, Pap B, Dobra G, Harmati M, Kormondi S, Pankotai T, Braunitzer G, Minarovits J, Sonkodi I, Urban E, Nemeth IB, Nagy K, Buzas K.
Pathol Oncol Res. 2019 Jul;25(3):1023-1033. doi: 10.1007/s12253-018-0457-x. Epub 2018 Jul 27.
19.
Coordinated activation of a cluster of MMP genes in response to UVB radiation.
Ujfaludi Z, Tuzesi A, Majoros H, Rothler B, Pankotai T, Boros IM.
Sci Rep. 2018 Feb 8;8(1):2660. doi: 10.1038/s41598-018-20999-6. PMID: 29422610
20.
TAF10 and TAF10b partially redundant roles during Drosophila melanogaster morphogenesis.
Pahi Z, Borsos BN, Vedelek B, Shidlovskii YV, Georgieva SG, Boros IM, Pankotai T.
Transcription. 2017;8(5):297-306. doi: 10.1080/21541264.2017.1327836. Epub 2017 Aug 25. PMID: 28841365
21.
The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export.
Kristó I, Bajusz C, Borsos BN, Pankotai T, Dopie J, Jankovics F, Vartiainen MK, Erdélyi M, Vilmos P.
Biochim Biophys Acta. 2017 May 27;1864(10):1589-1604. doi: 10.1016/j.bbamcr.2017.05.020. [Epub ahead of print] PMID: 28554770
22.
Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage.
Borsos BN, Huliák I, Majoros H, Ujfaludi Z, Gyenis Á, Pukler P, Boros IM, Pankotai T.
Sci Rep. 2017 Jan 19;7:40960. doi: 10.1038/srep40960.
23.
Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis.
Borsos BN, Pankotai T, Kovács D, Popescu C, Páhi Z, Boros IM.
Dev Biol. 2015 Aug 1;404(1):80-7. doi: 10.1016/j.ydbio.2015.04.020. Epub 2015 May 8. pubmed
24.
dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster.
Pahi Z, Kiss Z, Komonyi O, Borsos BN, Tora L, Boros IM, Pankotai T.
PLoS One. 2015 Nov 10;10(11):e0142226. doi: 10.1371/journal.pone.0142226. eCollection 2015. PMID: 26556600
25.
Nuclear position dictates DNA repair pathway choice.
Lemaître C, Grabarz A, Tsouroula K, Andronov L, Furst A, Pankotai T, Heyer V, Rogier M, Attwood KM, Kessler P, Dellaire G, Klaholz B, Reina-San-Martin B, Soutoglou E.
Genes Dev. 2014 Nov 15;28(22):2450-63. doi: 10.1101/gad.248369.114. Epub 2014 Nov 3. PMID:25366693
26.
Double strand breaks: hurdles for RNA polymerase II transcription?
Pankotai T, Soutoglou E.
Transcription. 2013 Jan-Feb;4(1):34-8. doi: 10.4161/trns.22879. Review. PMID: 23340208
27.
DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks.
Pankotai T, Bonhomme C, Chen D, Soutoglou E.
Nat Struct Mol Biol. 2012 Feb 12;19(3):276-82. doi: 10.1038/nsmb.2224. PMID: 22343725
The role of p53 in the DNA damage-related ubiquitylation of S2P RNAPII,
Barbara N Borsos, Vasiliki Pantazi, Zoltán G Páhi, Hajnalka Majoros, Zsuzsanna Ujfaludi, Ivett Berzsenyi, and Tibor Pankotai PLOS ONE doi: 10.1371/journal.pone.0267615
2.
Novel prognostic value of driver gene transcription signatures to characterise ccRCC,
Zsuzsanna Ujfaludi, Levente Kuthi, Gabriella Pankotai-Bodó, Bankó Sarolta Farkas Sükösd, Tibor Pankotai
Pathol. Oncol. Res. 28:1610345. doi: 10.3389/pore.2022.1610345
3.
The clinical significance of epigenetic and RNAPII variabilities occurring in clear cell renal cell carcinoma as a potential prognostic marker.
Ördög N, Borsos BN, Majoros H, Ujfaludi Z, Pankotai-Bodó G, Bankó S, Sükösd F, Kuthi L, Pankotai T.
Transl Oncol. 2022 Apr 10;20:101420. doi: 10.1016/j.tranon.2022.101420. Online ahead of print.
4.
Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster.
Páhi ZG, Kovács L, Szűcs D, Borsos BN, Deák P, Pankotai T.
Sci Rep. 2022 Apr 7;12(1):5870. doi: 10.1038/s41598-022-09703-x.
5.
Systematic overview on the most widespread techniques for inducing and visualizing the DNA double-strand breaks.
Berzsenyi I, Pantazi V, Borsos BN, Pankotai T.
Mutat Res Rev Mutat Res. 2021 Jul-Dec;788:108397. doi: 10.1016/j.mrrev.2021.108397. Epub 2021 Oct 29
6.
CDKL5 kinase controls transcription-coupled responses to DNA damage.
Khanam T, Muñoz I, Weiland F, Carroll T, Morgan M, Borsos BN, Pantazi V, Slean M, Novak M, Toth R, Appleton P, Pankotai T, Zhou H, Rouse J.
EMBO J. 2021 Dec 1;40(23):e108271. doi: 10.15252/embj.2021108271. Epub 2021 Oct 4.
7.
Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage.
Pantazi V, Berzsenyi I, Borsos BN, Pankotai T.
J Vis Exp. 2021 Aug 21;(174). doi: 10.3791/62175.
8.
SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response.
Majoros H, Borsos BN, Ujfaludi Z, Páhi ZG, Mórocz M, Haracska L, Boros IM, Pankotai T.
Int J Mol Sci. 2021 Aug 7;22(16):8500. doi: 10.3390/ijms22168500.
9.
Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria.
Ferenczi S, Solymosi N, Horváth I, Szeőcs N, Grózer Z, Kuti D, Juhász B, Winkler Z, Pankotai T, Sükösd F, Stágel A, Paholcsek M, Dóra D, Nagy N, Kovács KJ, Zanoni I, Szallasi Z.
Mol Ther Methods Clin Dev. 2020 Nov 20;20:218-226. doi: 10.1016/j.omtm.2020.11.010. eCollection 2021 Mar 12.
10.
Ubiquitylation-Mediated Fine-Tuning of DNA Double-Strand Break Repair.
Borsos BN, Majoros H, Pankotai T.
Cancers (Basel). 2020 Jun 18;12(6):1617. doi: 10.3390/cancers12061617.
11.
Emerging Roles of Post-Translational Modifications in Nucleotide Excision Repair.
Borsos BN, Majoros H, Pankotai T.
Cells. 2020 Jun 15;9(6):1466. doi: 10.3390/cells9061466.
12.
PARylation During Transcription: Insights into the Fine-Tuning Mechanism and Regulation
Zoltán G. Páhi, Barbara N. Borsos, Vasiliki Pantazi, Zsuzsanna Ujfaludi and Tibor Pankotai
Cancers 2020, 12(1), 183; https://doi.org/10.3390/cancers12010183
13.
Melanoma-Derived Exosomes Induce PD-1 Overexpression and Tumor Progression via Mesenchymal Stem Cell Oncogenic Reprogramming.
Gyukity-Sebestyén E, Harmati M, Dobra G, Németh IB, Mihály J, Zvara Á, Hunyadi-Gulyás É, Katona R, Nagy I, Horváth P, Bálind Á, Szkalisity Á, Kovács M, Pankotai T, Borsos B, Erdélyi M, Szegletes Z, Veréb ZJ, Buzás EI, Kemény L, Bíró T, Buzás K.
Front Immunol. 2019 Oct 18;10:2459. doi: 10.3389/fimmu.2019.02459. eCollection 2019
14.
Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells.
Harmati M, Gyukity-Sebestyen E, Dobra G, Janovak L, Dekany I, Saydam O, Hunyadi-Gulyas E, Nagy I, Farkas A, Pankotai T, Ujfaludi Z, Horvath P, Piccinini F, Kovacs M, Biro T, Buzas K.
Sci Rep. 2019 Oct 25;9(1):15329. doi: 10.1038/s41598-019-51778-6.
15.
Quantification of DNA damage induced repair focus formation via super-resolution dSTORM localization microscopy.
Varga D, Majoros H, Ujfaludi Z, Erdélyi M, Pankotai T.
Nanoscale. 2019 Aug 1;11(30):14226-14236. doi: 10.1039/c9nr03696b.
16.
WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.
Caron P, Pankotai T, Wiegant WW, Tollenaere MAX, Furst A, Bonhomme C, Helfricht A, de Groot A, Pastink A, Vertegaal ACO, Luijsterburg MS, Soutoglou E, van Attikum H.
Genes Dev. 2019 Jun 1;33(11-12):684-704. doi: 10.1101/gad.321943.118. Epub 2019 May 2.
17.
SerpinB2 is involved in cellular response upon UV irradiation.
Majoros H, Ujfaludi Z, Borsos BN, Hudacsek VV, Nagy Z, Coin F, Buzas K, Kovács I, Bíró T, Boros IM, Pankotai T.
Sci Rep. 2019 Feb 26;9(1):2753. doi: 10.1038/s41598-019-39073-w.
18.
Chicken or the Egg: Microbial Alterations in Biopsy Samples of Patients with Oral Potentially Malignant Disorders.
Decsi G, Soki J, Pap B, Dobra G, Harmati M, Kormondi S, Pankotai T, Braunitzer G, Minarovits J, Sonkodi I, Urban E, Nemeth IB, Nagy K, Buzas K.
Pathol Oncol Res. 2019 Jul;25(3):1023-1033. doi: 10.1007/s12253-018-0457-x. Epub 2018 Jul 27.
19.
Coordinated activation of a cluster of MMP genes in response to UVB radiation.
Ujfaludi Z, Tuzesi A, Majoros H, Rothler B, Pankotai T, Boros IM.
Sci Rep. 2018 Feb 8;8(1):2660. doi: 10.1038/s41598-018-20999-6. PMID: 29422610
20.
TAF10 and TAF10b partially redundant roles during Drosophila melanogaster morphogenesis.
Pahi Z, Borsos BN, Vedelek B, Shidlovskii YV, Georgieva SG, Boros IM, Pankotai T.
Transcription. 2017;8(5):297-306. doi: 10.1080/21541264.2017.1327836. Epub 2017 Aug 25. PMID: 28841365
21.
The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export.
Kristó I, Bajusz C, Borsos BN, Pankotai T, Dopie J, Jankovics F, Vartiainen MK, Erdélyi M, Vilmos P.
Biochim Biophys Acta. 2017 May 27;1864(10):1589-1604. doi: 10.1016/j.bbamcr.2017.05.020. [Epub ahead of print] PMID: 28554770
22.
Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage.
Borsos BN, Huliák I, Majoros H, Ujfaludi Z, Gyenis Á, Pukler P, Boros IM, Pankotai T.
Sci Rep. 2017 Jan 19;7:40960. doi: 10.1038/srep40960.
23.
Acetylations of Ftz-F1 and histone H4K5 are required for the fine-tuning of ecdysone biosynthesis during Drosophila metamorphosis.
Borsos BN, Pankotai T, Kovács D, Popescu C, Páhi Z, Boros IM.
Dev Biol. 2015 Aug 1;404(1):80-7. doi: 10.1016/j.ydbio.2015.04.020. Epub 2015 May 8. pubmed
24.
dTAF10- and dTAF10b-Containing Complexes Are Required for Ecdysone-Driven Larval-Pupal Morphogenesis in Drosophila melanogaster.
Pahi Z, Kiss Z, Komonyi O, Borsos BN, Tora L, Boros IM, Pankotai T.
PLoS One. 2015 Nov 10;10(11):e0142226. doi: 10.1371/journal.pone.0142226. eCollection 2015. PMID: 26556600
25.
Nuclear position dictates DNA repair pathway choice.
Lemaître C, Grabarz A, Tsouroula K, Andronov L, Furst A, Pankotai T, Heyer V, Rogier M, Attwood KM, Kessler P, Dellaire G, Klaholz B, Reina-San-Martin B, Soutoglou E.
Genes Dev. 2014 Nov 15;28(22):2450-63. doi: 10.1101/gad.248369.114. Epub 2014 Nov 3. PMID:25366693
26.
Double strand breaks: hurdles for RNA polymerase II transcription?
Pankotai T, Soutoglou E.
Transcription. 2013 Jan-Feb;4(1):34-8. doi: 10.4161/trns.22879. Review. PMID: 23340208
27.
DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks.
Pankotai T, Bonhomme C, Chen D, Soutoglou E.
Nat Struct Mol Biol. 2012 Feb 12;19(3):276-82. doi: 10.1038/nsmb.2224. PMID: 22343725
